The supplements that don't play nicely with your medicines

"It's natural" doesn't mean "it's free of consequences." A few common supplements have real effects on prescription medicines.

The usual suspects

St John's wort can blunt the pill, some antidepressants and blood thinners. High-dose fish oil and vitamin E nudge bleeding risk. Calcium and iron can stop certain antibiotics and thyroid tablets from absorbing.

Timing fixes some of it

Several clashes are about absorption, not chemistry — spacing a supplement a couple of hours from the medicine is often enough. Others mean picking one or the other.

Bring the bottles

Drop your supplements in next time you collect a script. A two-minute check is far cheaper than a problem, and we won't tell you to bin things that are genuinely helping.

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